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Chromatin Regulation
Laboratory Asifa Akhtar
The role of non-coding RNA in dosage-compensation
The role of the nuclear periphery in X chromosomal regulation
The role of the NSL complex in gene regulation
The function of the mammalian MSL complex
Developmental Immunology
Laboratory Thomas Boehm
Thymus development and function
Genetics of thymopoiesis and T cell development in vertebrates
Evolution of adaptive immune systems
Laboratory Ana Izcue
Role of the intestinal epithelium in shaping the immune response
Mechanisms of Immune Tolerance
Cellular & Molecular Immunology
Laboratory Rudolf Grosschedl
Regulatory Circuitries of B Lymphopoiesis
Stem cell pluripotency and higher-order chromatin structure
Laboratory Patrick Heun
Epigenetic Regulation of Chromosome Organization
Nuclear organization of centromeres
The role of PIAS in heterochromatin organization
Laboratory Simona Saccani
Molecular basis of promoter- & stimulus-specificity in NF-kB-dependent gene induction
Mechanisms underlying differing responses to NF-kB activation between cell types
Epigenetics
Laboratory Thomas Jenuwein
Epigenetic Control by Histone Methylation
Genome-wide distribution and function of the Suv39h enzymes
Laboratory Andrea Pichler
Regulation of sumoylation by its sole E2 enzyme Ubc9
Regulation of ubiquitination by the E2-enzyme E2-25K
Laboratory J. Andrew Pospisilik
Epigenetic Control of Complex Disease
Functional translation of epigenetic cues
Molecular Embryology
Emeritus Laboratory Rolf Kemler
Cell Adhesion in Mouse Development (Marc Stemmler)
Post-transcriptional control of ß-catenin and N-cadherin by microRNAs and RNA-binding proteins (Jennifer Winter)
The function of ß-catenin in embryonic stem (ES) cells and in development (Rolf Kemler)
Molecular Immunology
Laboratory Michael Reth
Signal Processes in B Cells: from Analysis to Synthesis
Studying B cell function in vivo with the Cre/loxP technique
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Laboratory Hassan Jumaa
Regulation of Proliferation and Differentiation of B cells
Inducible activation of oncogenic Syk isoforms
Role of FoxO transcription factors in Ig gene recombination
Laboratory Peter Nielsen
Gene Expression during B-cell Development
The role of Bob1 in regulating B-cell development
Spemann Laboratory
Laboratory Taro Fukao
The Role of microRNAs in the Hematopoietic and Immune System
Identification of microRNAs differentially regulated during DC differentiation
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